师资队伍

细胞生物学与生物物理学系

赵莉

日期:2020-08-11 点击数: 来源:

   名:

赵莉

 

      称:

副教授

最高学位:

博士研究生

   话:

18186861339

   件:

zhaoli2011@jlu.edu.cn

工作地点:

生命科学楼381

研究方向:

1. 计算结构生物学;2. 生物信息学;3. 计算机辅助药物设计

教育经历:

2001.09-2005.07 新葡的京集团8814 化学学院 学士

2005.09-2011.06 新葡的京集团8814 化学学院(理论化学研究所) 博士

工作经历:

2011.07-2016.09 新葡的京集团8814 新葡的京集团8814 讲师

2016.10-现在 新葡的京集团8814 新葡的京集团8814 副教授

2019.07-2020.07 美国波士顿大学 访问学者

荣誉称号:

 

研究成果:

承担项目:

国家基金委,自然科学基金重点项目子课题,2023.01-2026.12,90万,项目负责人

国家基金委,自然科学基金青年项目,2015.01-2017.12,25万,项目负责人

国家基金委,自然科学基金面上项目,2013.01-2016.12,80万,主要参加人

超分子结构与材料国家重点实验室,开放课题,2019.01-2019.122万,项目负责人

吉林省科技厅,国际合作项目,2022.01-2023.1210万,项目负责人

吉林省科技厅,吉林省科技发展计划青年基金,2013.01-2015.12,3万,项目负责人

吉林省教育厅,“十三五”科学技术研究项目(重点),2016.01-2018.12,5万,项目负责人

吉林省人社厅,吉林省博士后科研启动经费,2013.01-2014.12,3万,项目负责人

 

代表性文章:

1. Yanxin Xiang, Huanv Mao, Si-cheng Tong, Can Liu, Rui Yan, Li Zhao*, Linyong Zhu, Chunyan Bao*, ‘A Facile and Versatile Approach to Construct Photoactivated Peptide Hydrogels by Regulating Electrostatic Repulsio’, ACS Nano, 17 (2023), 5536-47.

2. Kuo Zhang, Zhong-yuan Lu*, Li Zhao*, 'Dissipative morphological characteristics of photo-responsive block copolymers driven by time-oscillatory irradiations: An in silico study', Polymer, 235 (2021), 124234-8.

3. Hui-min Gao, Li Zhao, Kun Liu, Zhong-yuan Lu*, ‘Polymerization-Induced Reassembly of Gemini Molecules toward Generating Porous Two-Dimensional Polymers’, Journal of Physical Chemistry Letters, 12 (2021), 2340-47.

4. Zhao-Yi Wang, Ning-Ning Zhang, Jin-Cheng Li, Jun Lu, Li Zhao, Xue-Dong Fang*, Kun Liu*, ‘Serum albumin guided plasmonic nanoassemblies with opposite chiralities’, Soft Matter, 26 (2021), 6298-9304.

5. Zhengfei Yu, Ye Liu, Jingxuan Zhu, Jiarui Han, Xiaopian Tian, Weiwei Han, Li Zhao*, 'Insights from Molecular Dynamics Simulations and Steered Molecular Dynamics Simulations to Exploit New Trends of the Interaction between Hif-1 Alpha and P300', Journal of Biomolecular Structure & Dynamics, 38 (2020), 1-12.

6. Bing-Yu Li, Li Zhao*, Zhong-Yuan Lu*, 'Microscopic Characteristics of Janus Nanoparticles Prepared Via a Grafting-from Reaction at the Immiscible Liquid Interface', Physical Chemistry Chemical Physics, 22 (2020), 5347-54.

7. Kuo Zhang, Duo Xu, Li Zhao*, Zhong-Yuan Lu*, 'Proper Adsorptive Confinement for Efficient Production of Cyclic Polymers: A Dissipative Particle Dynamics Study', Physical Chemistry Chemical Physics, 22 (2020), 18703-10.

8. Jian-Wei Wang, Li Zhao, Pu Tian*, 'Sequence Analysis of Insulin Degludec by Top-Down High Resolution Tandem Mass Spectrometry', Chinese Journal of Analytical Chemistry, 48 (2020), 1104-10.

9. Su-Min Ma, Li Zhao, Yong-Lei Wang*, You-Liang Zhu, Zhong-Yuan Lu*, 'The Coarse-Grained Models of Poly(Ethylene Oxide) and Poly(Propylene Oxide) Homopolymers and Poloxamers in Big Multipole Water (Bmw) and Martini Frameworks', Physical Chemistry Chemical Physics, 22 (2020), 15976-85.

10. Jingxuan Zhu, Renrui Qi, Yingrui Liu, Li Zhao*, Weiwei Han*, 'Mechanistic Insights into the Effect of Ligands on Structural Stability and Selectivity of Sulfotransferase 2a1 (Sult2a1)', Acs Omega, 4 (2019), 22021-34.

11. Duo Xu, Li Zhao, Kuo Zhang, Zhong-Yuan Lu*, ‘Dynamic self-assembly of block copolymers regulated by time-varying building block composition via reversible chemical reaction’, Science China-Chemistry, 62 (2019), 1666-74.

12. Jingxuan Zhu, Yan Wang, Xin Li, Weiwei Han*, Li Zhao*, 'Understanding the Interactions of Different Substrates with Wild-Type and Mutant Acylaminoacyl Peptidase Using Molecular Dynamics Simulations', Journal of Biomolecular Structure & Dynamics, 36 (2018), 4285-302.

13. Shanshan Guan#, Li Zhao#, Hanyong Jin, Ning Shan, Weiwei Han*, Song Wang*, Yaming Shan*, ‘Binding modes of phosphotriesterase-like lactonase complexed with -nonanoic lactone and paraoxon using molecular dynamics simulations’, Journal of Biomolecular Stryucture & Dynamics, 35 (2017), 273-86.

14. Yu Bao, Duo Xu, Lu Qian, Li Zhao, Zhong-yuan Lu, Shuxun Cui*, ‘Hydrophilicities of amylose and natural cellulose are regulated by the linkage between sugar rings’, Nanoscale, 9 (2017), 3382-3385. 

15. Jun Lu, Yi-Xin Chang, Ning-Ning Zhang, Ying Wei, Ai-Ju Li, Jia Tai, Yao Xue, Zhao-Yi Wang, Yang Yang, Li Zhao, Zhong-yuan Lu, Kun Liu*, ‘Chiral Plasmonic Nanochains via the Self-Assembly of Gold Nanorods and   Helical Glutathione Oligomers Facilitated by Cetyltrimethylammonium’ , ACS Nano, 11 (2017), 3463-3475.

 

学术会议报告:

1. 第十二届全国化学生物学学术会议(2023年),口头报告“Insight from structure of condensate formed by full-length FUS proteins: a coarse-grained molecular dynamics simulation study”。

2. 中国化学会2023年软物质理论计算与模拟学术会议(2023年),口头报告,“FUS protein condensate: insight from structure characteristics via coarse-grained molecular dynamics simulations”。